Protein tyrosine kinases :  from inhibitors to useful drugs / 
edited by Doriano Fabbro and Frank McCormick 
 - Totowa, N.J. :  Humana Press,  c2006 
 - xiii, 290 p. :  ill. (some col.) ;  23 cm. 
 - Cancer drug discovery and development ; .
 - Cancer drug discovery and development .
<br/><br/>Includes bibliographical references and index. 
<br/><br/>Protein tyrosine kinases as targets for cancer and other indications / Mark Pearson, Carlos Garcia-Echeverria, Doriano Fabbro -- Inhibitors of signaling interfaces: targeting Src homology 2 domains in drug discovery / Carlos Garcia-Echeverria -- PI 3-kinase inhibition: a target for therapeutic intervention / Peter M. Finan, Stephen G. Ward -- Src as a target for pharmaceutical intervention: potential and limitations / Mira Susa ... [et al.] -- Activated FLT3 receptor tyrosine kinase as a therapeutic target in leukemia / Blanca Scheijen, James D. Griffin -- JAK kinases in leukemias/lymphomas and multiple myeloma / Renate Burger, Martin Gramatzki -- Glivec (Gleevec, Imatinib, STI571): a targeted therapy for CML / Elisabeth Buchdunger, Renaud Capedeville -- Platelet-derived growth factor: normal function, role in disease, and applications of PDGF antagonists / Tobias Sjoblom ... [et al.] -- Structural biology of protein tyrosine kinases / Sandra W. Cowan-Jacob ... [et al.] -- Testing of signal transduction inhibitors in animal models of cancer / Terence O'Reilly, Robert Cozens -- Phosphoproteomics in drug discovery and development / Michel F. Moran. 
<br/><br/><label>ISBN: </label>158829384X (hbk.) 
<br/><br/><label>LCCN: </label>2005006248 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Protein-tyrosine kinase--Inhibitors Therapeutic use<br/>Cancer--Chemotherapy
<br/><br/><label>LC Class. No.: </label>RC271.P76