022290000a22003250004500 386823 20240227120317.0 090107s2006 njua f b 001 0 eng 2005006248 158829384X (hbk.) (Sirsi) 386823 UIAM eng RC271.P76 Protein tyrosine kinases : from inhibitors to useful drugs / edited by Doriano Fabbro and Frank McCormick Totowa, N.J. : Humana Press, c2006 xiii, 290 p. : ill. (some col.) ; 23 cm. rdacontent rdamedia rdacarrier Cancer drug discovery and development ; Includes bibliographical references and index. Protein tyrosine kinases as targets for cancer and other indications / Mark Pearson, Carlos Garcia-Echeverria, Doriano Fabbro -- Inhibitors of signaling interfaces: targeting Src homology 2 domains in drug discovery / Carlos Garcia-Echeverria -- PI 3-kinase inhibition: a target for therapeutic intervention / Peter M. Finan, Stephen G. Ward -- Src as a target for pharmaceutical intervention: potential and limitations / Mira Susa ... [et al.] -- Activated FLT3 receptor tyrosine kinase as a therapeutic target in leukemia / Blanca Scheijen, James D. Griffin -- JAK kinases in leukemias/lymphomas and multiple myeloma / Renate Burger, Martin Gramatzki -- Glivec (Gleevec, Imatinib, STI571): a targeted therapy for CML / Elisabeth Buchdunger, Renaud Capedeville -- Platelet-derived growth factor: normal function, role in disease, and applications of PDGF antagonists / Tobias Sjoblom ... [et al.] -- Structural biology of protein tyrosine kinases / Sandra W. Cowan-Jacob ... [et al.] -- Testing of signal transduction inhibitors in animal models of cancer / Terence O'Reilly, Robert Cozens -- Phosphoproteomics in drug discovery and development / Michel F. Moran. Protein-tyrosine kinase Inhibitors Therapeutic use 374109 Cancer Chemotherapy 20798 Fabbro, D. 374110 McCormick, Frank, 1950- 374111 Cancer drug discovery and development 15302 bib-snn lcc 267473 298061 0 0 0 0 GENERAL KIMC KIMC OPEN 2019-08-05 606.00 0 RC271P76P967F 2006 00001084721 2019-08-05 00:00:00 1 606.00 BOOKGEN