TY  - GEN
AU  - Fabbro,D.
AU  - McCormick,Frank
TI  - Protein tyrosine kinases: from inhibitors to useful drugs 
T2  - Cancer drug discovery and development
SN  - 158829384X (hbk.)
AV  - RC271.P76 
PY  - 2006///
CY  - Totowa, N.J.
PB  - Humana Press
KW  - Protein-tyrosine kinase
KW  - Inhibitors Therapeutic use
KW  - Cancer
KW  - Chemotherapy
N1  - Includes bibliographical references and index; Protein tyrosine kinases as targets for cancer and other indications / Mark Pearson, Carlos Garcia-Echeverria, Doriano Fabbro -- Inhibitors of signaling interfaces: targeting Src homology 2 domains in drug discovery / Carlos Garcia-Echeverria -- PI 3-kinase inhibition: a target for therapeutic intervention / Peter M. Finan, Stephen G. Ward -- Src as a target for pharmaceutical intervention: potential and limitations / Mira Susa ... [et al.] -- Activated FLT3 receptor tyrosine kinase as a therapeutic target in leukemia / Blanca Scheijen, James D. Griffin -- JAK kinases in leukemias/lymphomas and multiple myeloma / Renate Burger, Martin Gramatzki -- Glivec (Gleevec, Imatinib, STI571): a targeted therapy for CML / Elisabeth Buchdunger, Renaud Capedeville -- Platelet-derived growth factor: normal function, role in disease, and applications of PDGF antagonists / Tobias Sjoblom ... [et al.] -- Structural biology of protein tyrosine kinases / Sandra W. Cowan-Jacob ... [et al.] -- Testing of signal transduction inhibitors in animal models of cancer / Terence O'Reilly, Robert Cozens -- Phosphoproteomics in drug discovery and development / Michel F. Moran
ER  -